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MUM1 (Concentrate)

MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.

Full Name

Melanoma Associated Antigen (Mutated) 1

Function

Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Biological Process

Chromatin organization Source: UniProtKB
DNA repair Source: UniProtKB

Cellular Location

Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.

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Anti-MUM1 (Concentrate) antibodies

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Mouse Anti-MUM1 (Concentrate) Antibody (CB302) (CBMAB-AL302LY)

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Target: MUM1 (Concentrate)

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CB302

Application*: IVD

Mouse Anti-MUM1 (Concentrate) Antibody (CB301) (CBMAB-AL301LY)

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Target: MUM1 (Concentrate)

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CB301

Application*: IVD

Mouse Anti-MUM1 (Concentrate) Antibody (CB300) (CBMAB-AL300LY)

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Target: MUM1 (Concentrate)

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CB300

Application*: IVD

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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