MYEF2

MYEF2 (Myelin Expression Factor 2) is a Protein Coding gene. Diseases associated with MYEF2 include Loeys-Dietz Syndrome. Among its related pathways are Mitochondrial Gene Expression and Physiological and Pathological Hypertrophy of the Heart. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is HNRNPM.

Full Name

MYELIN EXPRESSION FACTOR 2

Function

Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA (By similarity).

Biological Process

Myotube differentiation Source: UniProtKB
Neuron differentiation Source: UniProtKB
Regulation of mRNA stability involved in response to oxidative stress Source: GO_Central
Regulation of transcription by RNA polymerase II Source: InterPro

Cellular Location

Nucleus

Anti-MYEF2 antibodies

Mouse Anti-MYEF2 Recombinant Antibody (CBFYM-2907) (CBMAB-M3102-FY)

Datasheet

SDS

Target: MYEF2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Cattle, Chicken, Cat, Human, Mouse, Rat

Clone: CBFYM-2907

Application*: E, IC, IH, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)