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NAPA

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene.
Full Name
NSF attachment protein alpha
Function
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
Biological Process
Apical protein localization Source: Ensembl
Brain development Source: Ensembl
Intracellular protein transport Source: GO_Central
Intra-Golgi vesicle-mediated transport Source: ProtInc
Membrane fusion Source: ProtInc
Neuron differentiation Source: Ensembl
Regulation of synaptic vesicle priming Source: GO_Central
SNARE complex disassembly Source: GO_Central
Synaptic transmission, glutamatergic Source: GO_Central
Synaptic vesicle priming Source: Ensembl
Cellular Location
Cell membrane

Anti-NAPA antibodies

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Target: NAPA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR7372
Application*: IF, P, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle
Clone: 15D4
Application*: F, IC, IF, P, IP, WB
Target: NAPA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR15047
Application*: IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-0979
Application*: E, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Cattle, Dog, Hamster
Clone: CBXS-0978
Application*: WB, P, IP
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Human, Rat
Clone: CBXS-5041
Application*: IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Cattle, Chicken, Human, Rat
Clone: CBXS-3753
Application*: WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle, Dog
Clone: CBXS-5800
Application*: WB, IH, IP, P
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Dog, Hamster, Human, Mouse, Rat
Clone: CBWJN-0455
Application*: P, IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Cattle
Clone: CBWJN-0385
Application*: WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Human, Rat
Clone: CBWJN-0384
Application*: IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Cattle, Chicken, Human, Mouse, Rat
Clone: 16D1
Application*: IA, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Cattle, Dog, Chicken, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Clone: 4E204
Application*: IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYC-A1009
Application*: IP, IH, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Cattle
Clone: CBYC-A1008
Application*: E, IP, WB
Target: NAPA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 4E4
Application*: E, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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