NCF2

NCF2 is neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
Full Name
Neutrophil Cytosolic Factor 2
Function
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Biological Process
Cellular defense response Source: ProtInc
Innate immune response Source: BHF-UCL
Phagocytosis Source: InterPro
Respiratory burst Source: BHF-UCL
Superoxide anion generation Source: UniProtKB
Superoxide metabolic process Source: BHF-UCL
Cellular Location
Cytoplasm
Involvement in disease
Granulomatous disease, chronic, autosomal recessive, 2 (CGD2):
A form of chronic granulomatous disease, a primary immunodeficiency characterized by severe recurrent bacterial and fungal infections, along with manifestations of chronic granulomatous inflammation. It results from an impaired ability of phagocytes to mount a burst of reactive oxygen species in response to pathogens.
View more

Anti-NCF2 antibodies

+ Filters
Loading...

Rabbit Anti-NCF2 Recombinant Antibody (CBYC-P114) (CBMAB-P0540-YC)

Go to compareCompare
Target: NCF2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYC-P114
Application*: IC, IF, P, IP, WB
Datasheet SDS

Mouse Anti-NCF2 Recombinant Antibody (29/p67phox) (CBMAB-P0539-YC)

Go to compareCompare
Target: NCF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 29/p67phox
Application*: WB, IF
Datasheet SDS

Rabbit Anti-NCF2 Recombinant Antibody (CBWJN-1208) (CBMAB-N1387-WJ)

Go to compareCompare
Target: NCF2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJN-1208
Application*: WB, IP, P, IC
Datasheet SDS

Rabbit Anti-NCF2 Recombinant Antibody (CBWJN-1207) (CBMAB-N1386-WJ)

Go to compareCompare
Target: NCF2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-1207
Application*: E
Datasheet SDS

Human NCF2 ELISA Kit (V2LY-0626-LY3998)

Go to compareCompare
Target: NCF2
Sensitivity: 0.0026 ng/mL
Detection Range: 0.005-1.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Human Recombinant NCF2 protein, GST Tag (V2LY-0526-LY5938)

Go to compareCompare
Target: NCF2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-526
Tag: GST Tag
Datasheet SDS

Human Recombinant NCF2 protein (V2LY-0526-LY5937)

Go to compareCompare
Target: NCF2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-526
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.