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NLE1

Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).

Full Name

Notchless Homolog 1

Function

Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).

Biological Process

Hematopoietic stem cell homeostasisIEA:Ensembl
Inner cell mass cell differentiationIEA:Ensembl
Kidney developmentIEA:Ensembl
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayIEA:Ensembl
Negative regulation of mitotic cell cycleIEA:Ensembl
Notch signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of canonical Wnt signaling pathwayIEA:Ensembl
Ribosomal large subunit assemblyManual Assertion Based On ExperimentIBA:GO_Central
Skeletal system morphogenesisIEA:Ensembl
SomitogenesisIEA:Ensembl

Cellular Location

Nucleus, nucleolus

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Anti-NLE1 antibodies

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Mouse Anti-NLE1 Recombinant Antibody (G-5) (CBMAB-N2635-WJ)

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Target: NLE1

Host: Mouse

Specificity: Human

Clone: G-5

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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