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Mouse Anti-NLE1 Recombinant Antibody (G-5) (CBMAB-N2635-WJ)

This product is a Mouse antibody that recognizes NLE1. The antibody G-5 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NLE1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
G-5
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Notchless Homolog 1
Introduction
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).
Entrez Gene ID
UniProt ID
Alternative Names
Notchless Homolog 1; Notchless Gene Homolog, (Drosophila); Notchless Homolog (Drosophila); Notchless Protein Homolog 1; Notchless Gene Homolog; NLE;
Function
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).
Biological Process
Hematopoietic stem cell homeostasisIEA:Ensembl
Inner cell mass cell differentiationIEA:Ensembl
Kidney developmentIEA:Ensembl
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayIEA:Ensembl
Negative regulation of mitotic cell cycleIEA:Ensembl
Notch signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of canonical Wnt signaling pathwayIEA:Ensembl
Ribosomal large subunit assemblyManual Assertion Based On ExperimentIBA:GO_Central
Skeletal system morphogenesisIEA:Ensembl
SomitogenesisIEA:Ensembl
Cellular Location
Nucleus, nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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