NLGN4Y

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Full Name

Neuroligin 4, Y-Linked

Function

Putative neuronal cell surface protein involved in cell-cell-interactions.

Biological Process

Chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
LearningManual Assertion Based On ExperimentIMP:BHF-UCL
Modulation of chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Neuron cell-cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Postsynaptic membrane assemblyManual Assertion Based On ExperimentIBA:GO_Central
Presynapse assemblyManual Assertion Based On ExperimentTAS:ARUK-UCL
Presynaptic membrane assemblyManual Assertion Based On ExperimentIBA:GO_Central
Social behaviorManual Assertion Based On ExperimentIMP:BHF-UCL
Synaptic vesicle endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Vocalization behaviorManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Cell membrane
Cell junction, synapse, postsynaptic density membrane

Topology

Extracellular: 44-676
Helical: 677-697
Cytoplasmic: 698-816