NRDC

This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

Nardilysin Convertase

Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.

Negative regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab
Positive regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:BHF-UCL

cell surface
cytosol
mitochondrion