OR2A2

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq]

Full Name

olfactory receptor, family 2, subfamily A, member 2

Function

Odorant receptor.

Cellular Location

Cell membrane

Topology

Extracellular: 1-24
Helical: 25-48
Cytoplasmic: 49-56
Helical: 57-78
Extracellular: 79-99
Helical: 100-119
Cytoplasmic: 120-138
Helical: 139-157
Extracellular: 158-195
Helical: 196-218
Cytoplasmic: 219-235
Helical: 236-258
Extracellular: 259-271
Helical: 272-291
Cytoplasmic: 292-310