PCDH1

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq]
Full Name
protocadherin 1
Function
May be involved in cell-cell interaction processes and in cell adhesion.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell junction
Cell membrane
Found at cell-cell boundaries and probably at cell-matrix boundaries.
Topology
Extracellular: 58-852
Helical: 853-873
Cytoplasmic: 874-1060
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Anti-PCDH1 antibodies

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Mouse Anti-PCDH1 Recombinant Antibody (2A11) (CBMAB-A6411-LY)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A11
Application*: WB, E
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (2E6) (CBMAB-A6409-LY)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2E6
Application*: WB, E
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (CBYC-P202) (CBMAB-P0959-YC)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Frog
Clone: CBYC-P202
Application*: WB, P
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (CBYC-P201) (CBMAB-P0958-YC)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P201
Application*: F
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (5D5) (CBMAB-P0957-YC)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5D5
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (4H2) (CBMAB-P0956-YC)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4H2
Application*: E, WB
Datasheet SDS

Mouse Anti-PCDH1 Recombinant Antibody (2E8) (CBMAB-P0955-YC)

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Target: PCDH1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E8
Application*: E, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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