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Mouse Anti-PCDH1 Recombinant Antibody (5D5) (CBMAB-P0957-YC)

Provided herein is a Mouse monoclonal antibody against Human Protocadherin 1. The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC-P, WB.
See all PCDH1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5D5
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IHC-P, WB

Basic Information

Immunogen
PCDH1 (NP_002578, 62-169 aa) partial recombinant protein with GST tag. Immunogen sequence: YKVPEEQPPN TLIGSLAADY GFPDVGHLYK LEVGAPYLRV DGKTGDIFTT ETSIDREGLR ECQNQLPGDP CILEFEVSIT DLVQNGSPRL LEGQIEVQDI NDNTPNFA
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 62-169

Target

Full Name
protocadherin 1
Introduction
PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Entrez Gene ID
5097
UniProt ID
Q08174
Alternative Names
Protocadherin 1; Cadherin-Like Protein 1; PC42; Protocadherin 1 (Cadherin-Like 1); Protocadherin 42; Protocadherin-42; Cadherin-Like 1; Protocadherin-1; PCDH42;
Function
May be involved in cell-cell interaction processes and in cell adhesion.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell junction
Cell membrane
Found at cell-cell boundaries and probably at cell-matrix boundaries.
Topology
Extracellular: 58-852
Helical: 853-873
Cytoplasmic: 874-1060
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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