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Mouse Anti-PCDH1 Recombinant Antibody (2E6) (CBMAB-A6409-LY)

The product is antibody recognizes PCDH1. The antibody 2E6 immunoassay techniques such as: WB, ELISA.
See all PCDH1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E6
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
PCDH1 (NP_002578, 62 a.a. ~ 169 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
protocadherin 1
Introduction
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq]
Entrez Gene ID
5097
UniProt ID
Q08174
Alternative Names
FLJ53887; MGC45991; PC42; PCDH42
Function
May be involved in cell-cell interaction processes and in cell adhesion.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell junction
Cell membrane
Found at cell-cell boundaries and probably at cell-matrix boundaries.
Topology
Extracellular: 58-852
Helical: 853-873
Cytoplasmic: 874-1060
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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