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PFKM

The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL; MIM 171860), and platelet (PFKP; MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively. The composition of the tetramers differs according to the tissue type. Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively. Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721]; Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM

Anti-PFKM antibodies

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Mouse Anti-PFKM Recombinant Antibody (CBYC-P310) (CBMAB-P1515-YC)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG2b
Cross Reactivity: Human, Mouse, Rat
Clone: CBYC-P310
Application*: E, WB

Mouse Anti-PFKM Recombinant Antibody (2F11) (CBMAB-P1514-YC)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG2a, κ
Cross Reactivity: Human
Clone: 2F11
Application*: E, WB

Mouse Anti-PFKM Recombinant Antibody (1D1) (CBMAB-1665-CN)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG2a, κ
Cross Reactivity: Human
Clone: 1D1
Application*: WB, E

Mouse Anti-PFKM Recombinant Antibody (CBYC-P311) (CBMAB-P1516-YC)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG
Cross Reactivity: Rat
Clone: CBYC-P311
Application*: WB, IC, P, C, E

Mouse Anti-PFKM Recombinant Antibody (CBXF-1962) (CBMAB-F1987-CQ)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Human
Clone: CBXF-1962
Application*: WB

Rabbit Anti-PFKM Recombinant Antibody (CBXF-1078) (CBMAB-F1024-CQ)

Target: PFKM
Host: Rabbit
Antibody Isotype: IgG
Cross Reactivity: Human, Mouse, Rat
Clone: CBXF-1078
Application*: WB, IF

Rabbit Anti-PFKM Recombinant Antibody (CBXF-1077) (CBMAB-F1023-CQ)

Target: PFKM
Host: Rabbit
Antibody Isotype: IgG
Cross Reactivity: Mouse, Rat, Human, Pig
Clone: CBXF-1077
Application*: WB, F, IF

Mouse Anti-PFKM Recombinant Antibody (CBXF-1014) (CBMAB-F1022-CQ)

Target: PFKM
Host: Mouse
Antibody Isotype: IgG2a
Cross Reactivity: Rat, Human
Clone: CBXF-1014
Application*: WB, E, IF
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)