PI15

This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq]

Full Name

peptidase inhibitor 15

Function

Serine protease inhibitor which displays weak inhibitory activity against trypsin (PubMed:8882727).
May play a role in facial patterning during embryonic development (By similarity).

Biological Process

Negative regulation of peptidase activityIEA:UniProtKB-KW

Cellular Location

Secreted

PTM

N-glycosylated.

Anti-PI15 antibodies

Rabbit Anti-PI15 Recombinant Antibody (BA0311) (CBMAB-0648CQ)

Datasheet

SDS

Target: PI15

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: BA0311

Application*: WB

Mouse Anti-PI15 Recombinant Antibody (CBYC-P363) (CBMAB-P1723-YC)

Datasheet

SDS

Target: PI15

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYC-P363

Application*: E, IH, WB

Mouse Anti-PI15 Recombinant Antibody (3B5) (CBMAB-P1721-YC)

Datasheet

SDS

Target: PI15

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3B5

Application*: E, P, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)