PIH1D1
PIH1D1 has ubiquitous expression in placenta (RPKM 13.7), lymph node (RPKM 13.6) and 25 other tissues.
Full Name
PIH1 Domain Containing 1
Function
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026).
Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451).
Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032).
Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451).
Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032).
Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
Biological Process
Box C/D snoRNP assemblyManual Assertion Based On ExperimentIMP:BHF-UCL
Chromatin remodelingManual Assertion Based On ExperimentIMP:UniProtKB
Epithelial cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Establishment of protein localization to chromatinManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 dimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 trimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H4-K16 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of glucose mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H3-K9 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H4 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein serine/threonine kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein-containing complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of TORC1 signalingManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription of nucleolar large rRNA by RNA polymerase IManual Assertion Based On ExperimentIMP:UniProtKB
Protein stabilization2 PublicationsIC:ComplexPortal
Regulation of histone H3-K4 methylationManual Assertion Based On ExperimentIMP:UniProtKB
rRNA processingManual Assertion Based On ExperimentIBA:GO_Central
SnoRNA localizationManual Assertion Based On ExperimentIMP:UniProtKB
TORC1 complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Chromatin remodelingManual Assertion Based On ExperimentIMP:UniProtKB
Epithelial cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Establishment of protein localization to chromatinManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 dimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H3-K9 trimethylationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of histone H4-K16 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of glucose mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H3-K9 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of histone H4 acetylationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein serine/threonine kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein-containing complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of TORC1 signalingManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of transcription of nucleolar large rRNA by RNA polymerase IManual Assertion Based On ExperimentIMP:UniProtKB
Protein stabilization2 PublicationsIC:ComplexPortal
Regulation of histone H3-K4 methylationManual Assertion Based On ExperimentIMP:UniProtKB
rRNA processingManual Assertion Based On ExperimentIBA:GO_Central
SnoRNA localizationManual Assertion Based On ExperimentIMP:UniProtKB
TORC1 complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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Anti-PIH1D1 antibodies
+ Filters
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CompareTarget: PIH1D1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P378
Application*: WB, E, IC, IF
Target: PIH1D1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4F5-1E10
Application*: E, IC, IF, IP, WB
Target: PIH1D1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E8
Application*: E, P, WB
Target: PIH1D1
Specificity: Human
Target: PIH1D1
Specificity: Human
Target: PIH1D1
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: G-10
Application*: WB, IP, IF, E
Target: PIH1D1
Host: Mouse
Specificity: Human
Clone: F-7
Application*: WB, IP, IF, E
Target: PIH1D1
Host: Mouse
Specificity: Human
Clone: A-10
Application*: WB, IP, IF, E
Target: PIH1D1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3355
Application*: E, WB
Target: PIH1D1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3287
Application*: E, IH, WB
Target: PIH1D1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3286
Application*: E, IF, IP, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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