PNMA1
PNMA1 is a neuron-and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors.
Full Name
PNMA1
Biological Process
Inflammatory response to antigenic stimulusBy SimilarityISS:UniProtKB
Positive regulation of apoptotic processISS:UniProtKB
Positive regulation of apoptotic processISS:UniProtKB
Cellular Location
Nucleus, nucleolus
In tumor cells, it is cytoplasmic.
In tumor cells, it is cytoplasmic.
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Anti-PNMA1 antibodies
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Target: PNMA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 1C3
Application*: WB, E
Target: PNMA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYC-P480
Application*: E, IH, WB
Target: PNMA1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4G6
Application*: WB
Target: PNMA1
Specificity: Human
Target: PNMA1
Specificity: Human
Target: PNMA1
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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