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PRKACG

Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit.

Full Name

protein kinase cAMP-activated catalytic subunit gamma

Function

Phosphorylates a large number of substrates in the cytoplasm and the nucleus.

Biological Process

High-density lipoprotein particle assemblyTAS:Reactome
Male gonad developmentManual Assertion Based On ExperimentTAS:ProtInc
Protein kinase A signalingManual Assertion Based On ExperimentIBA:GO_Central
Protein phosphorylationIEA:InterPro
Renal water homeostasisTAS:Reactome
SpermatogenesisManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

ciliary base
cytosol
nucleoplasm
nucleus

Involvement in disease

Bleeding disorder, platelet-type, 19 (BDPLT19):
A disorder characterized by increased bleeding tendency due to platelet dysfunction. Clinical features include epistaxis, hematomas, bleeding after tooth extraction, and menorrhagia.

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Anti-PRKACG antibodies

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Rabbit Anti-PRKACG Recombinant Antibody (EG1740) (CBMAB-EN2078-LY)

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Target: PRKACG

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1740

Application*: WB: 1:500~1:1000 ELISA: 1:10000

Mouse Anti-PRKACG Recombinant Antibody (2F3) (CBMAB-A7035-LY)

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Target: PRKACG

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2F3

Application*: E, E

Mouse Anti-PRKACG Recombinant Antibody (2E4) (CBMAB-P2801-YC)

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Target: PRKACG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2E4

Application*: E, WB, P, F

Mouse Anti-PRKACG Recombinant Antibody (13B644) (CBMAB-P2800-YC)

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Target: PRKACG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 13B644

Application*: E, F, IH, WB

Human Recombinant PRKACG, Active protein, GST Tag (V2LY-0526-LY6297)

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Target: PRKACG

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: Full Length

Tag: GST Tag

Mouse Anti-PRKACG Recombinant Antibody (CBT3658) (V2LY-0625-LY2762)

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Target: PRKACG

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT3658

Application*: IH, F

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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