PRPSAP2

PRPSAP2 is a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS.

Phosphoribosyl Pyrophosphate Synthetase Associated Protein 2

Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.

5-phosphoribose 1-diphosphate biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Bone developmentIEA:Ensembl
Nucleobase-containing compound metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Purine nucleotide biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central

cytoplasm
ribose phosphate diphosphokinase complex