PTP99A

Protein tyrosine phosphatase 99A (Ptp99A) is a transmembrane receptor tyrosine phosphatase. Its single mutants have no known phenotypes, but Ptp99A synergizes with Ptp69D to increase the penetrance of the Ptp69D motor axon defects. Ptp99A mutations also suppress the 'bypass' motor axon phenotype produced by Lar mutations.

Full Name

Ptp99A

Function

May play a key role in signal transduction and growth control. May have a role in the establishment of the intersegmental and segmental nerves.

Biological Process

Axonal defasciculationManual Assertion Based On ExperimentTAS:FlyBase
Defasciculation of motor neuron axonManual Assertion Based On ExperimentIGI:FlyBase
Motor neuron axon guidanceManual Assertion Based On ExperimentIGI:FlyBase
Peptidyl-tyrosine dephosphorylationManual Assertion Based On ExperimentIDA:FlyBase
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane

Topology

Extracellular: 29-394
Helical: 395-415
Cytoplasmic: 416-1301

Anti-PTP99A antibodies

Mouse Anti-PTP99A Recombinant Antibody (3A6) (CBMAB-0167-CN)

Datasheet

SDS

Target: PTP99A

Host: Mouse

Antibody Isotype: IgG1

Specificity: Common fruit fly

Clone: 3A6

Application*: E

Mouse Anti-PTP99A Recombinant Antibody (4C71B7) (CBMAB-0215-CN)

Datasheet

SDS

Target: PTP99A

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Common fruit fly

Clone: 4C71B7

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)