Mouse Anti-PTP99A Recombinant Antibody (4C71B7) (CBMAB-0215-CN)

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Basic Information

Host Animal
Mouse
Clone
4C71B7
Application
ELISA
Specificity
Common fruit fly
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Ptp99A
Introduction
Protein tyrosine phosphatase 99A (Ptp99A) is a transmembrane receptor tyrosine phosphatase. Its single mutants have no known phenotypes, but Ptp99A synergizes with Ptp69D to increase the penetrance of the Ptp69D motor axon defects. Ptp99A mutations also suppress the 'bypass' motor axon phenotype produced by Lar mutations.
Entrez Gene ID
UniProt ID
Alternative Names
CG11515; CG11516; CG11517; CG2005; CT6383; Dmel\CG11516; dptp99A; DPTP99A; DPTP[[99A]]; ptp99A; PTP99A; R-PTP 99A
Function
May play a key role in signal transduction and growth control. May have a role in the establishment of the intersegmental and segmental nerves.
Biological Process
Axonal defasciculationManual Assertion Based On ExperimentTAS:FlyBase
Defasciculation of motor neuron axonManual Assertion Based On ExperimentIGI:FlyBase
Motor neuron axon guidanceManual Assertion Based On ExperimentIGI:FlyBase
Peptidyl-tyrosine dephosphorylationManual Assertion Based On ExperimentIDA:FlyBase
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Extracellular: 29-394
Helical: 395-415
Cytoplasmic: 416-1301
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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