QPRT

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Full Name
Quinolinate Phosphoribosyltransferase
Function
Involved in the catabolism of quinolinic acid (QA).
Biological Process
Biological Process NAD biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process NAD metabolic processTAS:Reactome
Biological Process quinolinate catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
catalytic complex
cytoplasm
cytosol
extracellular exosome
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Anti-QPRT antibodies

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Rabbit Anti-QPRT Recombinant Antibody (RB34298) (CBMAB-1872-YC)

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Target: QPRT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RB34298
Application*: E, WB, IH
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (CBYC3-123) (CBMAB-1856-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC3-123
Application*: E, P, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (CBYC3-121) (CBMAB-1854-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC3-121
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (CBYC3-120) (CBMAB-1853-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC3-120
Application*: WB, P
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (7A8) (CBMAB-1850-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7A8
Application*: F, IH, P, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (5D11) (CBMAB-1849-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5D11
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (4E6) (CBMAB-1848-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E6
Application*: F, IH, P, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (4E5) (CBMAB-1847-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4E5
Application*: F, ICC, IF, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (4B4) (CBMAB-1846-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B4
Application*: F, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (4B3) (CBMAB-1845-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B3
Application*: WB, FC
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (3B3) (CBMAB-1844-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3B3
Application*: F, ICC, IF, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (2H4) (CBMAB-1843-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2H4
Application*: ICC, IF, WB
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (24C4) (CBMAB-1842-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 24C4
Application*: WB, F, E, ICC, IF
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (1C10) (CBMAB-1841-YC)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C10
Application*: F, IF, P, WB
Datasheet SDS

QPRT Matched Antibody Pair (952) (APMAB-952LY)

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Target: QPRT
Specificity: Human
Datasheet SDS

QPRT Matched Antibody Pair (951) (APMAB-951LY)

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Target: QPRT
Specificity: Human
Datasheet SDS

Mouse Anti-QPRT Recombinant Antibody (BA0420) (CBMAB-0767CQ)

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Target: QPRT
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BA0420
Application*: WB, P
Datasheet SDS

Rabbit Anti-QPRT Recombinant Antibody (BA0095) (CBMAB-0766CQ)

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Target: QPRT
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BA0095
Application*: WB, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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