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Mouse Anti-QPRT Recombinant Antibody (1C10) (CBMAB-1841-YC)

Provided herein is a Mouse monoclonal antibody against Human QPRT. The antibody, clone 1C10, can be used for immunoassay techniques, such as FC, IF, IHC-P, WB.
See all QPRT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C10
Antibody Isotype
IgG1
Application
FC, IF, IHC-P, WB

Basic Information

Immunogen
Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Quinolinate Phosphoribosyltransferase
Introduction
Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway.
Entrez Gene ID
UniProt ID
Alternative Names
QPRTase; HEL-S-90n
Function
Involved in the catabolism of quinolinic acid (QA).
Biological Process
Biological Process NAD biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process NAD metabolic processTAS:Reactome
Biological Process quinolinate catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
catalytic complex
cytoplasm
cytosol
extracellular exosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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