RALGPS2

RALGPS2 (Ral GEF With PH Domain And SH3 Binding Motif 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGPS1.
Full Name
Ral GEF with PH domain and SH3 binding motif 2
Function
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).
Biological Process
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:InterPro
Cellular Location
Cytoplasm
Cell membrane
Associates with membranes through the PH domain.
Involvement in disease
RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24.
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Anti-RALGPS2 antibodies

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Mouse Anti-RALGPS2 Recombinant Antibody (CBCNR-168) (CBMAB-R1252-CN)

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Target: RALGPS2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-168
Application*: WB
Datasheet SDS

Mouse Anti-RALGPS2 Recombinant Antibody (3F1) (CBMAB-R1251-CN)

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Target: RALGPS2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F1
Application*: E, IF, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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