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Mouse Anti-RALGPS2 Recombinant Antibody (3F1) (CBMAB-R1251-CN)

This product is a Mouse antibody that recognizes RALGPS2. The antibody 3F1 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all RALGPS2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3F1
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 282-387 form human RALGPS2 (NP_689876) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
Ral GEF with PH domain and SH3 binding motif 2
Introduction
RALGPS2 (Ral GEF With PH Domain And SH3 Binding Motif 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGPS1.
Entrez Gene ID
55103
UniProt ID
Q86X27
Alternative Names
Ral GEF With PH Domain And SH3 Binding Motif 2; Ral GEF With PH Domain And SH3-Binding Motif 2; RalA Exchange Factor RalGPS2; Ras-Specific Guanine Nucleotide-Releasing Factor RalGPS2; Ral-A Exchange Factor RalGPS2; DJ595C2.1;
Function
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).
Biological Process
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:InterPro
Cellular Location
Cytoplasm
Cell membrane
Associates with membranes through the PH domain.
Involvement in disease
RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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