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RGL2

RGL2 (Ral Guanine Nucleotide Dissociation Stimulator Like 2) is a Protein Coding gene. Diseases associated with RGL2 include Tumoral Calcinosis, Normophosphatemic, Familial and Familial Tumoral Calcinosis. Among its related pathways are G-protein signaling N-RAS regulation pathway and Cytoskeleton remodeling_RalA regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.

Full Name

ral guanine nucleotide dissociation stimulator-like 2

Function

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).

Biological Process

Biological Process negative regulation of cardiac muscle cell apoptotic processIEA:Ensembl
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:Ensembl

Cellular Location

cytosol
plasma membrane

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Anti-RGL2 antibodies

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Mouse Anti-RGL2 Recombinant Antibody (CBCNR-446) (CBMAB-R2415-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBCNR-446

Application*: WB

Mouse Anti-RGL2 Recombinant Antibody (9H3) (CBMAB-R2414-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 9H3

Application*: WB

Mouse Anti-RGL2 Recombinant Antibody (4D10) (CBMAB-R2412-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4D10

Application*: E, IF, WB

Mouse Anti-RGL2 Recombinant Antibody (4C1) (CBMAB-R2411-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4C1

Application*: WB

Mouse Anti-RGL2 Recombinant Antibody (10F2) (CBMAB-R2410-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 10F2

Application*: WB, IH

Mouse Anti-RGL2 Recombinant Antibody (10A11) (CBMAB-R2409-CN)

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Target: RGL2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 10A11

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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