RGL2

RGL2 (Ral Guanine Nucleotide Dissociation Stimulator Like 2) is a Protein Coding gene. Diseases associated with RGL2 include Tumoral Calcinosis, Normophosphatemic, Familial and Familial Tumoral Calcinosis. Among its related pathways are G-protein signaling N-RAS regulation pathway and Cytoskeleton remodeling_RalA regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.

ral guanine nucleotide dissociation stimulator-like 2

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).

Biological Process negative regulation of cardiac muscle cell apoptotic processIEA:Ensembl
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:Ensembl

cytosol
plasma membrane