RGL2

RGL2 (Ral Guanine Nucleotide Dissociation Stimulator Like 2) is a Protein Coding gene. Diseases associated with RGL2 include Tumoral Calcinosis, Normophosphatemic, Familial and Familial Tumoral Calcinosis. Among its related pathways are G-protein signaling N-RAS regulation pathway and Cytoskeleton remodeling_RalA regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.
Full Name
ral guanine nucleotide dissociation stimulator-like 2
Function
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
Biological Process
Biological Process negative regulation of cardiac muscle cell apoptotic processIEA:Ensembl
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:Ensembl
Cellular Location
cytosol
plasma membrane
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Anti-RGL2 antibodies

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Mouse Anti-RGL2 Recombinant Antibody (CBCNR-446) (CBMAB-R2415-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-446
Application*: WB
Datasheet SDS

Mouse Anti-RGL2 Recombinant Antibody (9H3) (CBMAB-R2414-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9H3
Application*: WB
Datasheet SDS

Mouse Anti-RGL2 Recombinant Antibody (4D10) (CBMAB-R2412-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4D10
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-RGL2 Recombinant Antibody (4C1) (CBMAB-R2411-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C1
Application*: WB
Datasheet SDS

Mouse Anti-RGL2 Recombinant Antibody (10F2) (CBMAB-R2410-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10F2
Application*: WB, IH
Datasheet SDS

Mouse Anti-RGL2 Recombinant Antibody (10A11) (CBMAB-R2409-CN)

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Target: RGL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10A11
Application*: WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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