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Mouse Anti-RGL2 Recombinant Antibody (10A11) (CBMAB-R2409-CN)

This product is a Mouse antibody that recognizes RGL2. The antibody 10A11 can be used for immunoassay techniques such as: WB.
See all RGL2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
10A11
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to aa. 547-777 of human RGL2 (NP_004752) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL

Target

Full Name
ral guanine nucleotide dissociation stimulator-like 2
Introduction
RGL2 (Ral Guanine Nucleotide Dissociation Stimulator Like 2) is a Protein Coding gene. Diseases associated with RGL2 include Tumoral Calcinosis, Normophosphatemic, Familial and Familial Tumoral Calcinosis. Among its related pathways are G-protein signaling N-RAS regulation pathway and Cytoskeleton remodeling_RalA regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.
Entrez Gene ID
5863
UniProt ID
O15211
Alternative Names
Ral Guanine Nucleotide Dissociation Stimulator Like 2; Ras-Associated Protein RAB2L; RalGDS-Like Factor; RalGDS-Like 2; RAB2L; Ral Guanine Nucleotide Dissociation Stimulator-Like 2;
Function
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
Biological Process
Biological Process negative regulation of cardiac muscle cell apoptotic processIEA:Ensembl
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:Ensembl
Cellular Location
cytosol
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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