Mouse Anti-RGL2 Recombinant Antibody (10F2) (CBMAB-R2410-CN)

Name: Mouse Anti-RGL2 Recombinant Antibody (10F2)
SKU: CBMAB-R2410-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

10F2

Application

WB, IHC

Immunogen

Human recombinant protein fragment corresponding to aa. 547-777 of human RGL2 (NP_004752) produced in E.coli

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

ral guanine nucleotide dissociation stimulator-like 2

Introduction

RGL2 (Ral Guanine Nucleotide Dissociation Stimulator Like 2) is a Protein Coding gene. Diseases associated with RGL2 include Tumoral Calcinosis, Normophosphatemic, Familial and Familial Tumoral Calcinosis. Among its related pathways are G-protein signaling N-RAS regulation pathway and Cytoskeleton remodeling_RalA regulation pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS.

Entrez Gene ID

5863

UniProt ID

O15211

Alternative Names

Ral Guanine Nucleotide Dissociation Stimulator Like 2; Ras-Associated Protein RAB2L; RalGDS-Like Factor; RalGDS-Like 2; RAB2L; Ral Guanine Nucleotide Dissociation Stimulator-Like 2;

Function

Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).

Biological Process

Biological Process negative regulation of cardiac muscle cell apoptotic processIEA:Ensembl
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of Ral protein signal transductionIEA:Ensembl

Cellular Location

cytosol
plasma membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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