S100A10

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]

S100 Calcium Binding Protein A10

Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

Biological Process membrane raft assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA transcription by RNA polymerase IIIEA:Ensembl
Biological Process positive regulation of bindingIEA:Ensembl
Biological Process positive regulation of exocytosis1 PublicationIC:ComplexPortal
Biological Process positive regulation of focal adhesion assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of plasma membrane repair1 PublicationIC:ComplexPortal
Biological Process positive regulation of plasminogen activationManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of substrate adhesion-dependent cell spreadingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein localization to plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of neurogenesisIEA:Ensembl
Biological Process vesicle budding from membraneManual Assertion Based On ExperimentIDA:UniProtKB

AnxA2-p11 complex
collagen-containing extracellular matrix
cytoplasm
extracellular exosome
extracellular region
extracellular space
extrinsic component of plasma membrane
membrane
nuclear matrix
plasma membrane
plasma membrane protein complex
RNA polymerase II transcription regulator complex