Rat Anti-S100A10 Recombinant Antibody (CBXS-1786) (CBMAB-S0113-CQ)

Name: Rat Anti-S100A10 Recombinant Antibody (CBXS-1786)
SKU: CBMAB-S0113-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

CBXS-1786

Application

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

S100 Calcium Binding Protein A10

Introduction

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.

Entrez Gene ID

20194

UniProt ID

Q3TC45

Alternative Names

42C; AA409961; AL024248; CAL12; CLP11; Cal1l; p10; p11

Function

Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

Biological Process

Biological Process membrane raft assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA transcription by RNA polymerase IIIEA:Ensembl
Biological Process positive regulation of bindingIEA:Ensembl
Biological Process positive regulation of exocytosis1 PublicationIC:ComplexPortal
Biological Process positive regulation of focal adhesion assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of plasma membrane repair1 PublicationIC:ComplexPortal
Biological Process positive regulation of plasminogen activationManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of substrate adhesion-dependent cell spreadingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein localization to plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of neurogenesisIEA:Ensembl
Biological Process vesicle budding from membraneManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

AnxA2-p11 complex
collagen-containing extracellular matrix
cytoplasm
extracellular exosome
extracellular region
extracellular space
extrinsic component of plasma membrane
membrane
nuclear matrix
plasma membrane
plasma membrane protein complex
RNA polymerase II transcription regulator complex

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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