SAFB2

The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.

Full Name

scaffold attachment factor B2

Function

Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.

Biological Process

Biological Process regulation of androgen receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Sertoli cell differentiationIEA:Ensembl

Cellular Location

Cytoplasm
Nucleus

Anti-SAFB2 antibodies

Mouse Anti-SAFB2 Recombinant Antibody (4H3) (CBMAB-A7884-LY)

Datasheet

SDS

Target: SAFB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4H3

Application*: WB, E

Mouse Anti-SAFB2 Recombinant Antibody (CBXS-5135) (CBMAB-S2353-CQ)

Datasheet

SDS

Target: SAFB2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-5135

Application*: WB, E, P, IF

Mouse Anti-SAFB2 Recombinant Antibody (CBXS-5229) (CBMAB-S2445-CQ)

Datasheet

SDS

Target: SAFB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: CBXS-5229

Application*: WB, IP, P, IF

Rabbit Anti-SAFB2 Recombinant Antibody (CBXS-1362) (CBMAB-S4220-CQ)

Datasheet

SDS

Target: SAFB2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBXS-1362

Application*: WB, P, IF

Mouse Anti-SAFB2 Recombinant Antibody (CBXS-2101) (CBMAB-S4866-CQ)

Datasheet

SDS

Target: SAFB2

Host: Mouse

Specificity: Human

Clone: CBXS-2101

Application*: WB, IP, IF, E

Mouse Anti-SAFB2 Recombinant Antibody (CBXS-3256) (CBMAB-S5997-CQ)

Datasheet

SDS

Target: SAFB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-3256

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)