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Mouse Anti-SAFB2 Recombinant Antibody (CBXS-5135) (CBMAB-S2353-CQ)

This product is a mouse antibody that recognizes SAFB2. The antibody CBXS-5135 can be used for immunoassay techniques such as: WB, ELISA, IHC-P, IF.
See all SAFB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5135
Antibody Isotype
IgG2b, κ
Application
WB, ELISA, IHC-P, IF

Basic Information

Immunogen
SAFB (NP_002958, 111 a.a.-201 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
scaffold attachment factor B2
Introduction
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.
Entrez Gene ID
UniProt ID
Alternative Names
Scaffold Attachment Factor B2; KIAA0138; SAF-B2;
Function
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
Biological Process
Biological Process regulation of androgen receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Sertoli cell differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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