SCGB1A1
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
Full Name
Secretoglobin Family 1A Member 1
Function
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Biological Process
Biological Process embryo implantationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process female pregnancy1 PublicationNAS:ProtInc
Biological Process negative regulation of interferon-gamma productionIEA:Ensembl
Biological Process negative regulation of interleukin-13 productionIEA:Ensembl
Biological Process negative regulation of interleukin-4 productionIEA:Ensembl
Biological Process negative regulation of interleukin-5 productionIEA:Ensembl
Biological Process negative regulation of T cell proliferationIEA:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of inflammatory responseIEA:Ensembl
Biological Process regulation of mRNA stabilityIEA:Ensembl
Biological Process response to cytokineIEA:Ensembl
Biological Process response to fibroblast growth factorIEA:Ensembl
Biological Process response to glucocorticoidIEA:Ensembl
Biological Process response to lipopolysaccharideIEA:Ensembl
Biological Process response to ozoneIEA:Ensembl
Biological Process response to silicon dioxideIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process signal transduction1 PublicationNAS:ProtInc
Biological Process T cell proliferationIEA:Ensembl
Biological Process female pregnancy1 PublicationNAS:ProtInc
Biological Process negative regulation of interferon-gamma productionIEA:Ensembl
Biological Process negative regulation of interleukin-13 productionIEA:Ensembl
Biological Process negative regulation of interleukin-4 productionIEA:Ensembl
Biological Process negative regulation of interleukin-5 productionIEA:Ensembl
Biological Process negative regulation of T cell proliferationIEA:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of inflammatory responseIEA:Ensembl
Biological Process regulation of mRNA stabilityIEA:Ensembl
Biological Process response to cytokineIEA:Ensembl
Biological Process response to fibroblast growth factorIEA:Ensembl
Biological Process response to glucocorticoidIEA:Ensembl
Biological Process response to lipopolysaccharideIEA:Ensembl
Biological Process response to ozoneIEA:Ensembl
Biological Process response to silicon dioxideIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process signal transduction1 PublicationNAS:ProtInc
Biological Process T cell proliferationIEA:Ensembl
Cellular Location
Secreted
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Anti-SCGB1A1 antibodies
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Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AY1E6
Application*: E, C, P, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Pig
Clone: CAP353
Application*: ICC, IHC, IP, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4A5-A11
Application*: WB, E
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F7
Application*: SE, E
Target: SCGB1A1
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H197
Application*: E, C, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B183
Application*: E, C, WB
Target: SCGB1A1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-96
Tag: His Tag
Target: SCGB1A1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-91
Tag: His Tag
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 21B2
Application*: E, F
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2262
Application*: F
Target: SCGB1A1
Specificity: Human
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0156
Application*: C, IA, P, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0953
Application*: E, WB, P, R
Target: SCGB1A1
Host: Mouse
Specificity: Rat
Clone: CBXS-0142
Application*: WB, IC, P, C, E
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0140
Application*: IH, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-5294
Application*: WB, IC, P, C, E, IP, IF, F
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4751
Application*: E, F, WB
Target: SCGB1A1
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4722
Application*: P, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4131
Application*: E, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-5667
Application*: E
Target: SCGB1A1
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2106
Application*: E, IH, WB
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-3092
Application*: E, F, WB
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXU-049
Application*: F
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXU-045
Application*: P
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXU-042
Application*: E
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXU-040
Application*: E
Target: SCGB1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXU-020
Application*: WB, F
Target: SCGB1A1
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLXU-162
Application*: WB, IH
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLXU-005
Application*: P
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rabbit
Clone: CBXU-170
Application*: WB, P, C, EM, E
Target: SCGB1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A8B8
Application*: F, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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