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SERPINA3

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
Full Name
Serpin Family A Member 3
Function
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Biological Process
Biological Process acute-phase responseIEA:UniProtKB-KW
Biological Process inflammatory response1 PublicationNAS:UniProtKB
Biological Process maintenance of gastrointestinal epithelium1 PublicationNAS:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of lipid metabolic process1 PublicationNAS:UniProtKB
Cellular Location
Secreted
PTM
N- and O-glycosylated.

Anti-SERPINA3 antibodies

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Mouse Anti-SERPINA3 Monoclonal Antibody (5G3C11) (CBMAB-1455-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 5G3C11
Application*: E, F, IH, P, WB

Mouse Anti-SERPINA3 Recombinant Antibody (10-118.2) (CBMAB-1796-CN)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10-118.2
Application*: E

Mouse Anti-SERPINA3 Recombinant Antibody (10-143.1) (CBMAB-1797-CN)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10-143.1
Application*: E

Rabbit Anti-SERPINA3 Recombinant Antibody (EPR14117(B)) (CBMAB-1798-CN)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EPR14117(B)
Application*: P, IP, WB

Rabbit Anti-SERPINA3 Recombinant Antibody (EPR14118(B)) (CBMAB-1799-CN)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EPR14118(B)
Application*: WB

Rabbit Anti-SERPINA3 Recombinant Antibody (EPR17088-68) (CBMAB-1800-CN)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EPR17088-68
Application*: WB, P, IF, IP

Rabbit Anti-SERPINA3 Recombinant Antibody (EPR5905) (CBMAB-1801-CN)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EPR5905
Application*: WB, IP

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-3098) (CBMAB-S5843-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: CBXS-3098
Application*: E

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-2765) (CBMAB-S5516-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-2765
Application*: E, IH, IP, WB

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-2708) (CBMAB-S5459-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2708
Application*: E, IH

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-1704) (CBMAB-S4542-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1704
Application*: WB

Rabbit Anti-SERPINA3 Recombinant Antibody (CBXS-1081) (CBMAB-S3970-CQ)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1081
Application*: EC

Rabbit Anti-SERPINA3 Recombinant Antibody (CBXS-1062) (CBMAB-S3953-CQ)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1062
Application*: E, ED

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-3845) (CBMAB-S1115-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3845
Application*: E

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-3844) (CBMAB-S1114-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3844
Application*: E

Rabbit Anti-SERPINA3 Recombinant Antibody (CBXS-3660) (CBMAB-S0939-CQ)

Datasheet SDS
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-3660
Application*: F, IC, IF

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-5977) (CBMAB-S0824-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5977
Application*: WB

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-5849) (CBMAB-S0704-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5849
Application*: P, WB

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-5822) (CBMAB-S0678-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5822
Application*: E

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-5610) (CBMAB-S0488-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5610
Application*: E, WB, IH

Mouse Anti-SERPINA3 Recombinant Antibody (AACT/1452) (CBMAB-S0299-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AACT/1452
Application*: WB, F, IF, P, MC

Mouse Anti-SERPINA3 Recombinant Antibody (CBXS-5769) (CBMAB-S0273-CQ)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: CBXS-5769
Application*: WB, F, E, IH, P, MC

Mouse Anti-SERPINA3 Recombinant Antibody (CF003) (CBMAB-FT461LY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CF003
Application*: ELISA, WB, IHC

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0426) (CBMAB-R0426-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0426
Application*: WB, E

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0425) (CBMAB-R0425-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0425
Application*: WB, E

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0424) (CBMAB-R0424-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0424
Application*: WB, E

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0423) (CBMAB-R0423-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0423
Application*: WB, E

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0422) (CBMAB-R0422-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0422
Application*: WB, E

Mouse Anti-SERPINA3 Monoclonal Antibody (CBFYR0421) (CBMAB-R0421-FY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0421
Application*: WB, E

Mouse Anti-SERPINA3 Recombinant Antibody (IHC501) (CBMAB-MA221-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: IHC501
Application*: IH

Mouse Anti-SERPINA3 Recombinant Antibody (3F5) (CBMAB-A7990-LY)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F5
Application*: SE, E

Mouse Anti-SERPINA3 Recombinant Antibody (CBYC-A1042) (CBMAB-A4754-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A1042
Application*: E

Mouse Anti-SERPINA3 Recombinant Antibody (ACT14C7) (CBMAB-A4753-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ACT14C7
Application*: C, P

Mouse Anti-SERPINA3 Recombinant Antibody (AACT/1451) (CBMAB-A4752-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AACT/1451
Application*: WB, P, IF, IC, F

Mouse Anti-SERPINA3 Recombinant Antibody (71A1) (CBMAB-A4751-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 71A1
Application*: IH, WB

Mouse Anti-SERPINA3 Recombinant Antibody (1E6) (CBMAB-A4749-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E6
Application*: E, P, IP, WB

Mouse Anti-SERPINA3 Recombinant Antibody (1C10) (CBMAB-A4748-YC)

Datasheet SDS
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C10
Application*: E, P

SERPINA3 Matched Antibody Pair (1057) (APMAB-1057LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1058) (APMAB-1058LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1059) (APMAB-1059LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1060) (APMAB-1060LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1061) (APMAB-1061LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1062) (APMAB-1062LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human

SERPINA3 Matched Antibody Pair (1063) (APMAB-1063LY)

Datasheet SDS
Target: SERPINA3
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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