SH2D2A

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.
Full Name
SH2 Domain Containing 2A
Function
Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.
Biological Process
Biological Process angiogenesisIEA:UniProtKB-KW
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process T cell proliferationIEA:Ensembl
Cellular Location
Cytoplasm
PTM
Phosphorylated on tyrosine residues.
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Anti-SH2D2A antibodies

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Mouse Anti-SH2D2A Recombinant Antibody (CBXS-5233) (CBMAB-S2448-CQ)

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Target: SH2D2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5233
Application*: F, WB
Datasheet SDS

Mouse Anti-SH2D2A Recombinant Antibody (CBXS-5065) (CBMAB-S2286-CQ)

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Target: SH2D2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5065
Application*: WB, F, IH, IF, P
Datasheet SDS

Mouse Anti-SH2D2A Recombinant Antibody (CBXS-4816) (CBMAB-S2042-CQ)

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Target: SH2D2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4816
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-SH2D2A Recombinant Antibody (CBXS-3889) (CBMAB-S1158-CQ)

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Target: SH2D2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3889
Application*: F, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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