SLC12A7

Full Name

Solute Carrier Family 12 Member 7

Function

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K+ uptake into Deiters' cells in the cochlea and contribute to K+ recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl- extrusion in the kidney and contribute to renal acidification (By similarity).

Biological Process

Biological Process ammonium import across plasma membraneISS:ARUK-UCL
Biological Process cell volume homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to glucose stimulusIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ion transportTAS:Reactome
Biological Process potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane