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SLC25A23

Full Name
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Function
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (PubMed:15123600).
May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (PubMed:15123600).
Acts as a regulator of mitochondrial calcium uptake via interaction with MCU and MICU1 (PubMed:24430870).
Biological Process
Biological Process calcium import into the mitochondrionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to calcium ionIEA:Ensembl
Biological Process mitochondrial calcium ion transmembrane transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of mitochondrial calcium ion concentrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of cellular hyperosmotic salinity responseManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of oxidative phosphorylationIEA:Ensembl
Biological Process regulation of sequestering of calcium ionIEA:Ensembl
Biological Process urea homeostasisIEA:Ensembl
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial intermembrane: 1-188
Helical: 189-206
Mitochondrial matrix: 207-243
Helical: 244-263
Mitochondrial intermembrane: 264-286
Helical: 287-300
Mitochondrial matrix: 301-336
Helical: 337-356
Mitochondrial intermembrane: 357-379
Helical: 380-397
Mitochondrial matrix: 398-436
Helical: 437-456
Mitochondrial intermembrane: 457-468

Anti-SLC25A23 antibodies

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Target: SLC25A23
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3058
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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