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Mouse Anti-SLC25A23 Recombinant Antibody (CBXS-3058) (CBMAB-S5804-CQ)

This product is a mouse antibody that recognizes SLC25A23. The antibody CBXS-3058 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC25A23 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3058
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa2-75 from human SLC25A23 (NP_077008) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Entrez Gene ID
UniProt ID
Alternative Names
Solute Carrier Family 25 Member 23; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 23; Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 2; Small Calcium-Binding Mitochondrial Carrier Protein 3; Mitochondrial ATP-Mg/Pi Carrier Protein 2; MCSC2; APC2;
Function
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (PubMed:15123600).
May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (PubMed:15123600).
Acts as a regulator of mitochondrial calcium uptake via interaction with MCU and MICU1 (PubMed:24430870).
Biological Process
Biological Process calcium import into the mitochondrionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to calcium ionIEA:Ensembl
Biological Process mitochondrial calcium ion transmembrane transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of mitochondrial calcium ion concentrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of cellular hyperosmotic salinity responseManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of oxidative phosphorylationIEA:Ensembl
Biological Process regulation of sequestering of calcium ionIEA:Ensembl
Biological Process urea homeostasisIEA:Ensembl
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial intermembrane: 1-188
Helical: 189-206
Mitochondrial matrix: 207-243
Helical: 244-263
Mitochondrial intermembrane: 264-286
Helical: 287-300
Mitochondrial matrix: 301-336
Helical: 337-356
Mitochondrial intermembrane: 357-379
Helical: 380-397
Mitochondrial matrix: 398-436
Helical: 437-456
Mitochondrial intermembrane: 457-468
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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