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SLC45A2

This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
solute carrier family 45, member 2
Function
Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity).
Biological Process
Biological Process developmental pigmentationIEA:Ensembl
Biological Process melanin biosynthetic processIEA:UniProtKB-KW
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process sucrose transportISS:ParkinsonsUK-UCL
Biological Process visual perceptionIEA:UniProtKB-KW
Cellular Location
Melanosome membrane
Involvement in disease
Albinism, oculocutaneous, 4 (OCA4):
A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus.
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Anti-SLC45A2 antibodies

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Mouse Anti-SLC45A2 Recombinant Antibody (2F4) (CBMAB-A8242-LY)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F4
Application*: WB, E
Datasheet SDS

Mouse Anti-SLC45A2 Recombinant Antibody (1B2) (CBMAB-A8241-LY)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1B2
Application*: WB, E
Datasheet SDS

Mouse Anti-SLC45A2 Recombinant Antibody (CBXS-2918) (CBMAB-S5667-CQ)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-2918
Application*: E, WB
Datasheet SDS

Mouse Anti-SLC45A2 Recombinant Antibody (CBXS-0481) (CBMAB-S3431-CQ)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-0481
Application*: SE, E, WB
Datasheet SDS

Mouse Anti-SLC45A2 (AA 1-636) Recombinant Antibody (CBXS-0480) (CBMAB-S3430-CQ)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-0480
Application*: E, WB
Datasheet SDS

Mouse Anti-SLC45A2 Recombinant Antibody (6/AIM-1) (CBMAB-A4785-YC)

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Target: SLC45A2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 6/AIM-1
Application*: WB, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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