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Mouse Anti-SLC45A2 Recombinant Antibody (6/AIM-1) (CBMAB-A4785-YC)

Provided herein is a Mouse monoclonal antibody against Human Solute Carrier Family 45 Member 2. The antibody can be used for immunoassay techniques, such as WB, IF.
See all SLC45A2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
6/AIM-1
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 45, member 2
Introduction
SLC45A2 is a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated wit
Entrez Gene ID
Human51151
Mouse22293
Rat310152
UniProt ID
HumanQ9UMX9
MouseP58355
RatD3ZR99
Alternative Names
ARK2; Aik2; AurB; Stk5; Stk12; AL022959; PPP1R48; Aim1; STK-1; AIM-1; IPL1; STK5; STK12; AIK2; ARK-2; AIRK2; aurkb-sv1; AIM1; Ark2; aurkb-sv2
Function
Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity).
Biological Process
Biological Process developmental pigmentationIEA:Ensembl
Biological Process melanin biosynthetic processIEA:UniProtKB-KW
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process sucrose transportISS:ParkinsonsUK-UCL
Biological Process visual perceptionIEA:UniProtKB-KW
Cellular Location
Melanosome membrane
Involvement in disease
Albinism, oculocutaneous, 4 (OCA4):
A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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