Mouse Anti-SLC45A2 Recombinant Antibody (6/AIM-1) (CBMAB-A4785-YC)

Name: Mouse Anti-SLC45A2 Recombinant Antibody (6/AIM-1)
SKU: CBMAB-A4785-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

6/AIM-1

Application

WB, IF

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 45, member 2

Introduction

SLC45A2 is a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated wit

Entrez Gene ID

Human	51151
Mouse	22293
Rat	310152

UniProt ID

Human	Q9UMX9
Mouse	P58355
Rat	D3ZR99

Alternative Names

ARK2; Aik2; AurB; Stk5; Stk12; AL022959; PPP1R48; Aim1; STK-1; AIM-1; IPL1; STK5; STK12; AIK2; ARK-2; AIRK2; aurkb-sv1; AIM1; Ark2; aurkb-sv2

Function

Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity).

Biological Process

Biological Process developmental pigmentationIEA:Ensembl
Biological Process melanin biosynthetic processIEA:UniProtKB-KW
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process sucrose transportISS:ParkinsonsUK-UCL
Biological Process visual perceptionIEA:UniProtKB-KW

Cellular Location

Melanosome membrane

Involvement in disease

Albinism, oculocutaneous, 4 (OCA4):
A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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