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Mouse Anti-SLC45A2 Recombinant Antibody (CBXS-2918) (CBMAB-S5667-CQ)

This product is a mouse antibody that recognizes SLC45A2. The antibody CBXS-2918 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC45A2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2918
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa1-636 from human SLC45A2 (AAH03597) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 45, member 2
Introduction
This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
51151
UniProt ID
Q9UMX9
Alternative Names
Solute Carrier Family 45 Member 2; Melanoma Antigen AIM1; Protein AIM-1; AIM1; MATP; Membrane-Associated Transporter Protein; Solute Carrier Family 45, Member 2;
Function
Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity).
Biological Process
Biological Process developmental pigmentationIEA:Ensembl
Biological Process melanin biosynthetic processIEA:UniProtKB-KW
Biological Process response to stimulusIEA:UniProtKB-KW
Biological Process sucrose transportISS:ParkinsonsUK-UCL
Biological Process visual perceptionIEA:UniProtKB-KW
Cellular Location
Melanosome membrane
Involvement in disease
Albinism, oculocutaneous, 4 (OCA4):
A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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