SLIT3

The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene.

slit homolog 3 (Drosophila)

May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.

Biological Process aortic valve morphogenesisISS:BHF-UCL
Biological Process apoptotic process involved in luteolysisManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process atrioventricular valve morphogenesisISS:BHF-UCL
Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to hormone stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of chemokine-mediated signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of gene expressionIEA:Ensembl
Biological Process response to cortisolManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process Roundabout signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process ventricular septum morphogenesisISS:BHF-UCL

Secreted