SLIT3
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene.
Full Name
slit homolog 3 (Drosophila)
Function
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
Biological Process
Biological Process aortic valve morphogenesisISS:BHF-UCL
Biological Process apoptotic process involved in luteolysisManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process atrioventricular valve morphogenesisISS:BHF-UCL
Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to hormone stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of chemokine-mediated signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of gene expressionIEA:Ensembl
Biological Process response to cortisolManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process Roundabout signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process ventricular septum morphogenesisISS:BHF-UCL
Biological Process apoptotic process involved in luteolysisManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process atrioventricular valve morphogenesisISS:BHF-UCL
Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to hormone stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of chemokine-mediated signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of gene expressionIEA:Ensembl
Biological Process response to cortisolManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process Roundabout signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process ventricular septum morphogenesisISS:BHF-UCL
Cellular Location
Secreted
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Anti-SLIT3 antibodies
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Target: SLIT3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3C5
Application*: SE, E
Target: SLIT3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D11
Application*: WB, E
Target: SLIT3
Host: Mouse
Specificity: Rat
Clone: CBXS-2642
Application*: E, IC, IH, WB
Target: SLIT3
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXS-1941
Application*: IH
Target: SLIT3
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBXS-0506
Application*: E, WB
Target: SLIT3
Host: Mouse
Specificity: Human
Clone: CBXS-4811
Application*: WB, IP, E
Target: SLIT3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-3962
Application*: E
Target: SLIT3
Host: Mouse
Specificity: Rat
Clone: CBFYM-3131
Application*: WB, IC, P, C, E
Target: SLIT3
Host: Mouse
Specificity: Human
Clone: CBFYM-3130
Application*: WB, IC, P, C, E
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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