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Mouse Anti-SLIT3 Recombinant Antibody (CBFYM-3130) (CBMAB-M3327-FY)

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Basic Information

Host Animal
Mouse
Clone
CBFYM-3130
Application
WB, ICC, IHC-P, IHC-Fr, ELISA
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
slit homolog 3 (Drosophila)
Introduction
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
6586
UniProt ID
O75094
Alternative Names
Slit Guidance Ligand 3; Multiple Epidermal Growth Factor-Like Domains Protein 5; Multiple EGF-Like Domains Protein 5; Slit-3; SLIL2; MEGF5; Slit (Drosophila) Homolog 3
Function
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
Biological Process
Biological Process aortic valve morphogenesisISS:BHF-UCL
Biological Process apoptotic process involved in luteolysisManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process atrioventricular valve morphogenesisISS:BHF-UCL
Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to hormone stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell growthManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of chemokine-mediated signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of gene expressionIEA:Ensembl
Biological Process response to cortisolManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process Roundabout signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process ventricular septum morphogenesisISS:BHF-UCL
Cellular Location
Secreted
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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