SNX12
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Full Name
Sorting Nexin 12
Function
May be involved in several stages of intracellular trafficking.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process late endosome to Golgi transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of early endosome to late endosome transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of gene expressionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of protein catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of protein processingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of protein transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process late endosome to Golgi transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of early endosome to late endosome transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of gene expressionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of protein catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of protein processingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of protein transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Membrane
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Anti-SNX12 antibodies
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Target: SNX12
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2C10
Application*: WB, E
Target: SNX12
Sensitivity: 0.0092 ng/mL
Detection Range: 0.02-3.8 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SNX12
Specificity: Human
Target: SNX12
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2855
Application*: E, WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-0623
Application*: SE, E, WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5246
Application*: P, WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5154
Application*: WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5143
Application*: WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4737
Application*: WB, IH
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4437
Application*: WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3853
Application*: P, WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5922
Application*: WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5915
Application*: P, WB
Target: SNX12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5880
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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