Spock3

Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM
Full Name
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
Function
May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.
Biological Process
Biological Process negative regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.
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Anti-Spock3 antibodies

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Mouse Anti-SPOCK3 Recombinant Antibody (1A10) (CBMAB-A8544-LY)

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Target: SPOCK3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1A10
Application*: SE, E
Datasheet SDS

Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659) (CBMAB-S5411-CQ)

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Target: SPOCK3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-2659
Application*: E
Datasheet SDS

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1686) (CBMAB-T0736-YJ)

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Target: Spock3
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJT-1686
Application*: WB, IP
Datasheet SDS

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1685) (CBMAB-T0735-YJ)

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Target: Spock3
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJT-1685
Application*: EC
Datasheet SDS

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1684) (CBMAB-T0734-YJ)

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Target: Spock3
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-1684
Application*: F, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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