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Spock3

Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM

Full Name

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

Function

May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.

Biological Process

Biological Process negative regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl

Cellular Location

Secreted, extracellular space, extracellular matrix

PTM

Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.

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Anti-Spock3 antibodies

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Mouse Anti-SPOCK3 Recombinant Antibody (1A10) (CBMAB-A8544-LY)

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Target: SPOCK3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1A10

Application*: SE, E

Mouse Anti-SPOCK3 Recombinant Antibody (1A10)

Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659) (CBMAB-S5411-CQ)

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Target: SPOCK3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-2659

Application*: E

Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659)

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1686) (CBMAB-T0736-YJ)

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Target: Spock3

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBYJT-1686

Application*: WB, IP

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1686)

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1685) (CBMAB-T0735-YJ)

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Target: Spock3

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBYJT-1685

Application*: EC

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1685)

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1684) (CBMAB-T0734-YJ)

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Target: Spock3

Host: Rat

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYJT-1684

Application*: F, WB

Rat Anti-Spock3 Recombinant Antibody (CBYJT-1684)

Mouse Recombinant SPOCK3 protein, His Tag (V2LY-0526-LY8934)

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Target: SPOCK3

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 1-436

Tag: His Tag

Mouse Recombinant SPOCK3 protein, His Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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