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Mouse Anti-SPOCK3 Recombinant Antibody (1A10) (CBMAB-A8544-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1A10
Antibody Isotype
IgG2b, κ
Application
sELISA, ELISA

Basic Information

Immunogen
SPOCK3 (NP_058646, 132 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
Introduction
Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM
Entrez Gene ID
50859
UniProt ID
Q9BQ16
Alternative Names
HSAJ1454; TES-3
Function
May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.
Biological Process
Biological Process negative regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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