Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659) (CBMAB-S5411-CQ)

Name: Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659)
SKU: CBMAB-S5411-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2659

Application

ELISA

Immunogen

Partial recombinant corresponding to aa132-231 from human SPOCK3 (NP_058646) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

Introduction

This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Entrez Gene ID

50859

UniProt ID

Q9BQ16

Alternative Names

SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 3; Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan (Testican) 3; TICN3; SPARC/Osteonectin, CWCV, And Kazal-Like Domains Proteoglycan 3; Testican-3; HSAJ1454; TES-3;

Function

May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.

Biological Process

Biological Process negative regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl

Cellular Location

Secreted, extracellular space, extracellular matrix

PTM

Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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