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Mouse Anti-SPOCK3 Recombinant Antibody (CBXS-2659) (CBMAB-S5411-CQ)

This product is a mouse antibody that recognizes SPOCK3. The antibody CBXS-2659 can be used for immunoassay techniques such as: ELISA.
See all SPOCK3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2659
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa132-231 from human SPOCK3 (NP_058646) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
Introduction
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Entrez Gene ID
50859
UniProt ID
Q9BQ16
Alternative Names
SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 3; Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan (Testican) 3; TICN3; SPARC/Osteonectin, CWCV, And Kazal-Like Domains Proteoglycan 3; Testican-3; HSAJ1454; TES-3;
Function
May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.
Biological Process
Biological Process negative regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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