SSR2

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq]

Full Name

signal sequence receptor, beta (translocon-associated protein beta)

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Biological Process

Cotranslational protein targeting to membrane

Cellular Location

Endoplasmic reticulum membrane

Topology

Lumenal: 18-149
Helical: 150-169
Cytoplasmic: 170-183

Anti-SSR2 antibodies

Mouse Anti-SSR2 Recombinant Antibody (4C1) (CBMAB-A8613-LY)

Datasheet

SDS

Target: SSR2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4C1

Application*: WB, E

Mouse Anti-SSR2 Recombinant Antibody (CBXS-6117) (CBMAB-S2952-CQ)

Datasheet

SDS

Target: SSR2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-6117

Application*: E, F, IF, WB

Mouse Anti-SSR2 Recombinant Antibody (CBXS-4994) (CBMAB-S2216-CQ)

Datasheet

SDS

Target: SSR2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4994

Application*: E, IC, IF, WB

Mouse Anti-SSR2 Recombinant Antibody (CBXS-4689) (CBMAB-S0248-CQ)

Datasheet

SDS

Target: SSR2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-4689

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)