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SSR2

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq]

Full Name

signal sequence receptor, beta (translocon-associated protein beta)

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Biological Process

Cotranslational protein targeting to membrane

Cellular Location

Endoplasmic reticulum membrane

Topology

Lumenal: 18-149
Helical: 150-169
Cytoplasmic: 170-183

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Anti-SSR2 antibodies

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Mouse Anti-SSR2 Recombinant Antibody (4C1) (CBMAB-A8613-LY)

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Target: SSR2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4C1

Application*: WB, E

Mouse Anti-SSR2 Recombinant Antibody (CBXS-6117) (CBMAB-S2952-CQ)

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Target: SSR2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-6117

Application*: E, F, IF, WB

Mouse Anti-SSR2 Recombinant Antibody (CBXS-4994) (CBMAB-S2216-CQ)

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Target: SSR2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4994

Application*: E, IC, IF, WB

Mouse Anti-SSR2 Recombinant Antibody (CBXS-4689) (CBMAB-S0248-CQ)

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Target: SSR2

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-4689

Application*: WB, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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