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Mouse Anti-SSR2 Recombinant Antibody (4C1) (CBMAB-A8613-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4C1
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SSR2 (NP_003136.1, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
signal sequence receptor, beta (translocon-associated protein beta)
Introduction
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq]
Entrez Gene ID
6746
UniProt ID
P43308
Alternative Names
DKFZp686F19123; HSD25; TLAP; TRAP-BETA; TRAPB
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Biological Process
Cotranslational protein targeting to membrane
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 18-149
Helical: 150-169
Cytoplasmic: 170-183
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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