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Mouse Anti-SSR2 Recombinant Antibody (CBXS-4689) (CBMAB-S0248-CQ)

This product is a mouse antibody that recognizes SSR2. The antibody CBXS-4689 can be used for immunoassay techniques such as: WB, ELISA.
See all SSR2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4689
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
Recombinant human SSR2 (18-149aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
signal sequence receptor, beta (translocon-associated protein beta)
Introduction
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.
Entrez Gene ID
6746
UniProt ID
P43308
Alternative Names
Signal Sequence Receptor Subunit 2; Signal Sequence Receptor, Beta (Translocon-Associated Protein Beta); Signal Sequence Receptor Subunit Beta; Translocon-Associated Protein Beta; TRAP-BETA; SSR-Beta;
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Biological Process
Cotranslational protein targeting to membrane
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 18-149
Helical: 150-169
Cytoplasmic: 170-183
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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