TCEAL1
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq]
Full Name
transcription elongation factor A (SII)-like 1
Function
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
Cellular Location
Nucleus
PTM
Phosphorylation of Ser-38 and Ser-39 is critical for transcriptional repression.
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Anti-TCEAL1 antibodies
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Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B9
Application*: WB, E
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B5
Application*: WB, E
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-2238
Application*: WB
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2235
Application*: WB, IH
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-2234
Application*: E, WB
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-2233
Application*: WB
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2232
Application*: WB
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2231
Application*: WB
Target: TCEAL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2230
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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